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This book reviews new promising drug targets for Neglected Tropical Diseases (NTDs), with a special focus on antiprotozoal drugs against trpyanosomatids Trypanosoma cruzi and Leishmania spp. The book offers a comprehensive overview of the most recent studied targets, and it outlines classical and new treatments and delivery strategies. Expert contributors describe new methods of analysis and bio-prospecting for new compounds, and provide a critical perspective of the translational process used in the research and development of new drug candidates.
This comprehensive edited book on microbial prospective discusses the innovative approaches and investigation strategies, as well as provides a broad spectrum of the cutting-edge research on the processing, properties and technological developments of microbial products and their applications. Microbes finds very important applications in our lives including industries and food processing. They are widely used in the fermentation of beverages, processing of dairy products, production of pharmaceuticals, chemicals, enzymes, proteins and biomaterials; conversion of biomass into fuel, fuel cell technology, health and environmental sectors. Some of these products are produced commercially, while others are potentially valuable in biotechnology. Microorganisms are considered invaluable in research as model organisms. This is a useful compilation for students and researchers in microbiology, biotechnology and chemical industries.
Sex therapist, Chad White helps a variety of clients work through their sexual issues. The only problem is, he doesn’t have anybody to work through his own. At home, his once-sexually driven wife isn’t interested in passionate sex anymore and his need to connect to a woman is becoming problematic for their marriage. These marital problems become even more evident when he finds himself drawn to Olive, a patient of his that’s afraid of intimacy. The two forge a flirtatious friendship that ultimately him to make tough decisions about both his marriage and about what and whom he ultimately wants in life.
The scandal and mysterious events surrounding the tragic drowning of a young woman, as Ted Kennedy drove his car off the infamous bridge, are revealed in the new movie starring Jason Clarke as Ted Kennedy and Kate Mara as Mary Jo Kopechne. Not only did this event take the life of an aspiring political strategist and Kennedy insider, but it ultimately changed the course of presidential history forever. Through true accounts, documented in the inquest from the investigation in 1969, director John Curran and writers Andrew Logan and Taylor Allen, intimately expose the broad reach of political power, the influence of America’s most celebrated family; and the vulnerability of Ted Kennedy, the youngest son, in the shadow of his family legacy.
Cliff is the leader of an enterprise he runs with his two best friends. His time in the life has taken a toll and he’s eager to run away with his girlfriend Stephanie. They have a plan, but things take a dark twisted turn.
Ainsley McGregor is enjoying small-town routines until murder disrupts again. When a respected local watchmaker is found dead, the close-knit community is shaken, and suspicion quickly spreads among friends, customers, and competitors.
Follows an aspiring actress working on a U.S. military base that simulates an Iraqi war zone.
High in the Sierra Nevada Mountains of California, a local sheriff finds world skateboard champion, Paul McGuiness’ abandoned hearse parked at a remote alpine lake, a surfboard floating on the surface of the freezing water, but no trace of his body. Rumors immediately go viral that the troubled sports icon has committed suicide or overdosed on drugs from the relentless pressure being put on him to maintain his number one position as world champion. Paul’s brother and manager, Bruce McGuiness, soon becomes haunted with the fear that he has caused the death of his younger sibling by having pushed him too hard to compete. Stricken with guilt and shame, he sets out on an epic road trip with four of Paul’s best friends to restore his missing brother’s honor and skateboard legacy. What begins as an adventure of a lifetime to make skateboard history, quickly turns into an ominous battle for survival as Bruce discovers that what happened to brother, is now happening to him.
John Davidson: diagnosed with Tourette’s syndrome at a young age which alienated him from his peers, he struggled with a condition few people had witnessed.
The film will explore society’s obsessions with the pursuit of happiness and will be presented by Mark Manson alongside Disappointment Panda, a character from the book whose superpower is to tell people the harsh truth.
